http://www.journalajrimps.com/index.php/AJRIMPS/issue/feed Asian Journal of Research in Medical and Pharmaceutical Sciences 2020-06-07T04:03:01+00:00 Asian Journal of Research in Medical and Pharmaceutical Scie contact@journalajrimps.com Open Journal Systems <p style="text-align: justify;"><strong>Asian Journal of Research in Medical and Pharmaceutical Sciences&nbsp;(ISSN: 2457-0745)</strong>&nbsp;aims to publish research papers, reviews and short communications in the areas of&nbsp;medical and pharmaceutical sciences. This is a quality controlled, peer-reviewed, open access INTERNATIONAL journal. This journal will not only publish traditional full research reports, including short communications, but also this journal will publish reports/articles on all stages of the research process like study protocols, pilot studies and pre-protocols. This journal is novelty attracting, open-minded, peer-reviewed medical periodical, designed to serve as a perfectly new platform for both mainstream and new ground shaking works as long as they are technically correct and scientifically motivated.&nbsp;The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> http://www.journalajrimps.com/index.php/AJRIMPS/article/view/30140 Anticancer Effect of Moringa oleifera Leaf Extract on A2780 Ovarian Cancer Cell Line 2020-06-07T04:03:01+00:00 Tolosa Daniel Angasa Yinuo Hong Ziqiang Ding Xianfeng Ding bdd114@163.com <p>In this study we investigated anticancer effect of <em>Moringa oleifera</em> leaf extract on A2780 ovarian cancer cell line. The leave of <em>Moringa oleifera</em> were grinded into powder and the phytochemicals were extracted using 80% ethanol. For fractionation and partitioning process four kinds of solvents were used in order: Petroleum ether, Dichloromethane, Ethyl acetate and Water extract until the extract is colorless or lightened. For cell proliferation assay all samples were dissolved in DimethylSulfoxide. Anticancer effect of <em>Moringa oleifera</em> were tested on A2780 ovarian cell line with four different extracts using 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide. The final result showed that on Petroleum Ether, Dichloromethane and Ethyl Acetate extracts as the concentration increases from 1 µg/ml, 2 µg/ml, 3 µg/ml, 4 µg/ml inhibited A2780, despite that in water extracts when the concentration decreases the inhibitory effect increases, however, Dichloromethane Extract has higher anticancer effect on A2780 ovarian cancer cell line with insignificant cytotoxicity to the normal cell.</p> 2020-04-21T00:00:00+00:00 ##submission.copyrightStatement##